MK-677 vs Tesamorelin: side-by-side comparison
Ibutamoren · MK677 · Nutrobal
An oral ghrelin mimetic that stimulates GH pulses. Technically not a peptide but a non-peptide agonist of the ghrelin receptor that increases growth hormone and IGF-1 levels.
Egrifta
A GHRH analog FDA-approved for reducing visceral adipose tissue. Particularly effective at targeting stubborn abdominal and visceral fat.
4 / 10 natty scale / 4
Same lane
Both sit in the same class, but they are pointed at different goals: MK-677 at recovery, bulking, Tesamorelin at cutting.
The tape
Core ratings
The same three rulers every entry on the site is scored with, read head to head.
Natty scale
1 natural · 10 heavy
Effectiveness
Documented effect · of 5Δ1.5
Side-effect severity
Documented burden · of 5Δ0.5
Cost side
Body-load fingerprint
Where each one actually lands its strain, on the calculator's thirteen channels. Tap a row for what it means and which labs track it.
Cardiometabolic
Organ strain
Hormonal
Systemic
Injection & site care
Bars show strain at each one's typical protocol, not your dose. ≈ marks values inferred from side-effect data or category rather than hand-graded. For your numbers, run the calculator.
Logistics
The vitals
Benefit side
What each is for
Shared goals carry both dots; a goal with one dot belongs to that side alone.
Run for
Documented upside
- Oral administration (no injections)
- Improved sleep quality
- Increased appetite
- Elevated IGF-1 levels
- Enhanced recovery
Run for
Documented upside
- Targeted visceral fat loss
- FDA-approved with clinical data
- Improved trunk fat distribution
- Natural GH pattern preservation
- Well-studied safety profile
The downsides
Side effects, aligned
Each entry's documented side effects, sorted onto the same body systems so the gaps and the overlaps are visible. Tap any effect for the detail.
None documented
None documented
The exit
Hormonal fallout & recovery
What each does to your own hormone axis while on, and what leaving it costs.
MK-677
Does not suppress testosterone. No PCT required.
Tesamorelin
Does not suppress natural hormone production. No PCT required.
Read-out
How they separate
- 01
Enhancement
They land at almost the same point on the natty scale (4/10 vs 4/10): a similar distance beyond natural.
- 02
Side-effect bill
MK-677's documented side-effect severity is heavier (3/5 vs 2.5/5). The body-load fingerprint above shows where that weight actually lands.
- 03
Body load
The widest gap at typical protocols is estrogen load (MK-677 4/10 vs 0/10), then blood sugar (MK-677 7.8/10 vs 4/10).
- 04
Coming off
Neither requires PCT: both leave the natural testosterone axis running.
- 05
Logistics
MK-677 runs as oral, Tesamorelin as subcutaneous; typical runs are 8-12 weeks vs 12-26 weeks.
- 06
Tested athletes
Both are WADA-prohibited: neither belongs anywhere near tested competition.
Generated from each entry's data file. Descriptive, not a recommendation; nothing here is medical advice.