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HGH vs Tesamorelin: side-by-side comparison

Growth Hormone

Somatropin · Human Growth Hormone · Growth Hormone

Direct replacement of the body's growth hormone for recovery, fat loss, and anti-aging. Provides systemic benefits including improved body composition, sleep, skin quality, and healing.

7.0/10 natty
Full breakdown →
VS
GH Secretagogue

Egrifta

A GHRH analog FDA-approved for reducing visceral adipose tissue. Particularly effective at targeting stubborn abdominal and visceral fat.

4.0/10 natty
Full breakdown →

7 / 10 natty scale / 4

Same lane

Both sit in the same class and are run for cutting. This is a like-for-like comparison: read the gaps as real trade-offs.

The tape

Core ratings

The same three rulers every entry on the site is scored with, read head to head.

HGHTesamorelin
7.0

Natty scale

1 natural · 10 heavyΔ3

4.0
4.0

Effectiveness

Documented effect · of 5Δ0.5

4.5
3.0

Side-effect severity

Documented burden · of 5Δ0.5

2.5

Cost side

Body-load fingerprint

Where each one actually lands its strain, on the calculator's thirteen channels. Tap a row for what it means and which labs track it.

HGHTesamorelin

Cardiometabolic

Organ strain

Hormonal

Systemic

Injection & site care

Bars show strain at each one's typical protocol, not your dose. marks values inferred from side-effect data or category rather than hand-graded. For your numbers, run the calculator.

Logistics

The vitals

HGHTesamorelin
Growth Hormone
Class
GH Secretagogue
Subcutaneous
Routematch
Subcutaneous
2-10 IU/dayDaily subcutaneous injection, typically morning (fasted, for fat loss) or split AM/PM at higher doses
Typical dose
1.3-2 mg/dayOnce daily subcutaneous injection
2-4 hours
Half-life
8-11 minutes
12-52 weeks
Typical run
12-26 weeks
Prescription only
Legal statusmatch
Prescription only
ProhibitedS2. Peptide Hormones, Growth Factors, Related Substances and Mimetics
WADAmatch
ProhibitedS2. Peptide Hormones, Growth Factors, Related Substances and Mimetics

Benefit side

What each is for

Shared goals carry both dots; a goal with one dot belongs to that side alone.

HGHTesamorelin
RecoveryCuttingLongevity

Run for

Fat LossPromotes lipolysis and mobilization of stored body fat.
Recovery EnhancementAccelerates recovery from training and injuries.
Anti-AgingImproves skin quality, sleep, and overall well-being.
Synergy with AASEnhances results when combined with anabolic steroids.

Documented upside

  • Significant fat loss
  • Enhanced recovery and healing
  • Improved sleep quality
  • Better skin elasticity and appearance
  • Increased collagen synthesis
+1 more on the full page

Run for

Visceral Fat ReductionSpecifically targets stubborn abdominal and visceral fat stores.
Body CompositionImproves overall body composition with focus on midsection.

Documented upside

  • Targeted visceral fat loss
  • FDA-approved with clinical data
  • Improved trunk fat distribution
  • Natural GH pattern preservation
  • Well-studied safety profile

The downsides

Side effects, aligned

Each entry's documented side effects, sorted onto the same body systems so the gaps and the overlaps are visible. Tap any effect for the detail.

HGHTesamorelin
Blood pressure & water
Blood sugar

None documented

Injection site
Other documented effects

The exit

Hormonal fallout & recovery

What each does to your own hormone axis while on, and what leaving it costs.

HGHTesamorelin
Not required
PCT
Not required
While-on only
What sticks
While-on only

HGH

Does not suppress natural hormone production in a way that requires PCT.

Tesamorelin

Does not suppress natural hormone production. No PCT required.

Read-out

How they separate

  1. 01

    Enhancement

    HGH sits 3 points higher on the natty scale (7/10 vs 4/10): a bigger step beyond natural at its typical protocol.

  2. 02

    Side-effect bill

    HGH's documented side-effect severity is heavier (3/5 vs 2.5/5). The body-load fingerprint above shows where that weight actually lands.

  3. 03

    Body load

    The widest gap at typical protocols is heart structure (HGH 5.5/10 vs 0/10), then blood sugar (HGH 7.8/10 vs 4/10).

  4. 04

    Coming off

    Neither requires PCT: both leave the natural testosterone axis running.

  5. 05

    Logistics

    typical runs are 12-52 weeks vs 12-26 weeks.

  6. 06

    Tested athletes

    Both are WADA-prohibited: neither belongs anywhere near tested competition.

Generated from each entry's data file. Descriptive, not a recommendation; nothing here is medical advice.