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Masteron

Also known as: Drostanolone, Mast, Drostanolone Propionate, Drostanolone Enanthate, Mast P, Mast E

6
1 · Natty510 · Enhanced

Lower numbers = closer to natural. Higher numbers = more enhanced.

Why this rating?

Masteron is primarily a cosmetic finisher rather than a mass builder (rat-assay anabolic:androgenic ratio of roughly 62-130:25-40). While it provides noticeable hardening and definition at competition-level leanness on typical doses (300-600mg/week), community and clinical-adjacent consensus consistently describes it as adding little mass on its own. Its main value is aesthetic hardening/dryness and SHBG binding to free up other compounds in a stack. Still a clearly supraphysiological androgen dose no natural athlete could replicate, but less transformative alone than mass-building steroids like testosterone or primobolan, closer to Anavar in its standalone muscle-building contribution.

Overview

A DHT-derived compound used primarily as a cosmetic finisher for competition. Provides muscle hardness, dryness, and acts as a mild anti-estrogen.

Purpose & Use Cases

Competition Prep

Used in the final weeks before competition to enhance muscle hardness and dryness.

Estrogen Masking

Acts as a mild AI, helping to control estrogen-related side effects.

Aesthetic Enhancement

Improves muscle definition and vascularity for a more polished look.

Benefits

  • Enhanced muscle hardness and density
  • Increased dryness and vascularity
  • Anti-estrogenic properties
  • Increases free testosterone via SHBG binding
  • No water retention
  • Relatively mild side effect profile

Good to Know

What "DHT-prone" means and why Masteron is high-risk for hair

Male-pattern baldness is driven by DHT binding to genetically sensitive scalp follicles. Being "DHT-prone" means your follicles are unusually sensitive to androgens. Masteron is a DHT derivative and one of the harshest compounds on the hairline, if you are prone it can accelerate loss quickly, and unlike a testosterone cycle that loss cannot be softened with finasteride.

Finasteride does nothing for DHT-derivatives

Finasteride/dutasteride block the 5-alpha-reductase enzyme that converts testosterone into DHT. Masteron and the other DHT-derived steroids (Winstrol, Anavar, Primobolan, Proviron) are already past that step, so there is nothing to block. 5-AR inhibitors only protect the scalp/prostate on compounds that convert to DHT via 5-AR, mainly testosterone.

A finisher, not a builder

Masteron adds little mass. Its value is cosmetic hardness/dryness that only shows up when already lean (under ~12% body fat), plus SHBG binding that frees up more testosterone. At higher body fat you will barely notice it.

Dosage Guidelines

Experience LevelDosage Range
Beginner300400 mg/week
Intermediate400500 mg/week
Advanced500600 mg/week
Frequency
Propionate: EOD minimum, daily preferred for stable levels; Enanthate: 2x/week
Typical Cycle Length
610 weeks
Notes

Works best when already lean (under 12% body fat). Effects less noticeable at higher body fat.

Side Effects

Severe Hair Loss

very common
Severity
4/5

As a DHT derivative, it accelerates hair loss significantly in predisposed individuals.

Mitigation

Consider avoiding if hair is a priority. Topical treatments have limited effectiveness.

Acne

common
Severity
2/5

Increased sebum production leading to acne.

Mitigation

Good hygiene; benzoyl peroxide treatments.

Prostate Enlargement

uncommon
Severity
3/5

Can exacerbate prostate issues due to DHT activity.

Mitigation

Monitor PSA levels; avoid if prostate issues exist.

General Mitigation Strategies

Monitor PSA levels for prostate health. Standard PCT required after cycle. Note that 5-alpha-reductase inhibitors (finasteride/dutasteride) do NOT reduce Masteron's androgenic hair/prostate effects. It is already a DHT derivative with no 5-AR conversion to block.

Support Supplements

Ancillary supplements commonly run alongside Masteron to manage side effects, support the target tissue, or fill nutrient demands it creates.

Lipid support (omega-3 + citrus bergamot)

Key

DHT-derivatives are hard on cholesterol, Masteron notably suppresses HDL. Omega-3 helps triglycerides; citrus bergamot lowers LDL via statin-like flavonoids.

Dose
Omega-3 2-4 g/day; citrus bergamot 500-1,000 mg/day
Timing
With meals
When
Lipid strain compounds when Masteron is stacked with orals or other dry compounds, monitor a full lipid panel.

Blood pressure support (telmisartan / low-dose tadalafil)

Manages blood-pressure rise from a cycle; tadalafil also supports erectile function and endothelial health.

Dose
Telmisartan 20-40 mg/day; tadalafil 2.5-5 mg/day
Timing
Daily; titrate to readings

Post Cycle Therapy (PCT)

⚠️PCT Required

Standard SERM PCT (e.g. Nolvadex 40/40/20/20). Start timing by ester: ~2 weeks after the last Enanthate pin, ~3-4 days after Propionate. Masteron does not aromatize, so estrogen rebound is not the concern; restoring natural testosterone is.

How It Works

Masteron is a DHT derivative that does not aromatize and has anti-estrogenic properties. It binds to SHBG, freeing up more testosterone. Provides a hardening effect by reducing water retention.

Hormonal & Androgenic Profile

Aromatizes (→ estrogen)none
Natural test suppressionmoderate
Hair loss risk (DHT-prone)high
Liver toxicitynone
DHT-derivativeYes
Progestogenic (19-nor)No
Anabolic : Androgenic ratio

62-130:25-40 (drostanolone): moderate-to-high on paper, but rat-assay anabolic scores are known to overstate real-world mass-building potency; in practice it is regarded as one of the milder steroids for building muscle

Estrogen control

Does not aromatize and acts as a mild anti-estrogen itself, no AI needed. Can actually help blunt estrogen from aromatizing stack-mates.

DHT / 5-AR & finasteride

Already a DHT derivative, so finasteride/dutasteride are useless here. There is no testosterone-to-DHT conversion to block. Androgenic hair/prostate effects cannot be mitigated with 5-AR inhibitors.

Cardiovascular impact

Strongly suppresses HDL cholesterol like most DHT-derivatives; no water retention or estrogenic BP rise, but monitor lipids closely.

Fundamentals

Common Stacks

  • Masteron + Testosterone + Trenbolone - Competition prep stack
  • Masteron + Testosterone + Anavar - Cutting stack
  • Masteron + Primobolan - Mild cutting stack

WADA Status

Prohibited by WADA
Category: S1. Anabolic Agents
In-Competition: ProhibitedOut-of-Competition: Prohibited

Drostanolone (Masteron) is explicitly prohibited as an anabolic androgenic steroid.

References

Last updated: July 18, 2026