Methyl-1-Testosterone
Also known as: M1T, Methyldihydroboldenone, 17α-Methyl-1-testosterone, Methyl-1-Testosterone, SC-11195
Lower numbers = closer to natural. Higher numbers = more enhanced.
Why this rating?
M1T is the 17α-methylated (orally active) version of 1-testosterone / dihydroboldenone (DHB), a strongly anabolic, non-aromatizing oral steroid that is regarded as one of the harshest of the prohormone/designer-steroid era. Because DHB is already a potent androgen, methylating it produces dramatic dry strength and mass at low doses but with severe hepatotoxicity, marked lethargy and lipid damage. That mix of strong physique effect and heavy toxicity places it near the top of the scale, rated 9.
Overview
A potent oral designer steroid from the prohormone era, the 17α-methyl derivative of 1-testosterone (dihydroboldenone/DHB). It delivers hard, dry strength and mass at small doses but is notorious for severe liver toxicity, debilitating lethargy and lipid damage. Sold over-the-counter as a "prohormone" until it was scheduled as a controlled substance.
Important Warnings
- •One of the most hepatotoxic prohormone-era oral steroids. Keep any use very short
- •Never combine with another 17-alkylated oral: combined liver strain can cause serious injury
- •Debilitating lethargy is common and often forces early termination
- •Always run a testosterone base: M1T makes no estrogen and is suppressive
- •Finasteride/dutasteride cannot protect hair here. It is already 5α-reduced
Purpose & Use Cases
Dry Strength & Mass
Produces rapid, hard, non-estrogenic strength and size at low doses. The appeal that made it a prohormone-era staple.
Short Recomp Blast
Used in very short runs for a lean-mass and strength kick without water retention.
Benefits
- Strong dry mass and strength at low doses
- Non-aromatizing: no estrogenic water retention or gyno
- Orally active
- Hard, dense look without bloat
Good to Know
It is methylated DHB, a strong androgen made oral
M1T = 17α-methyl-1-testosterone, i.e. the oral version of 1-testosterone / dihydroboldenone (DHB). Because DHB is already a potent injectable androgen, adding the 17α-methyl group to make it oral produces big dry gains at small doses, but that same methyl group is exactly what makes it so hepatotoxic.
Non-aromatizing, so dry: but no estrogen benefits
The 1(2) double bond of its parent blocks aromatase, so M1T makes no estrogen: no gyno, no bloat, no AI needed. But estrogen is what protects libido, mood, joints and cholesterol, so an estrogen-free oral run solo feels flat and wrecks lipids. Hence a testosterone base is standard.
Lethargy and liver toxicity are the headline drawbacks
Two things keep M1T niche: debilitating lethargy that often forces people to stop early, and severe hepatotoxicity that mandates very short cycles, no other orals, and TUDCA plus bloodwork. Finasteride is useless for its hair effects. It is already 5α-reduced, like Masteron and DHB.
Muscle memory keeps some benefit after you stop
The dry tissue M1T builds is retained better than watery Dbol-style gains, and any effective androgen adds myonuclei that persist long after the drug clears ("muscle memory"). A past M1T run nudges your "natural" ceiling upward, but the trade is one of the harshest liver/lipid profiles of any oral.
Dosage Guidelines
| Experience Level | Dosage Range |
|---|---|
| Beginner | 0 – 0 mg/day |
| Intermediate | 10 – 15 mg/day |
| Advanced | 15 – 20 mg/day |
There is no medical dosing for M1T. The low-milligram ranges shown are community-reported prohormone-era practice, not from a medical source. It is very hepatotoxic, so runs are kept very short (2-4 weeks) and it should never be stacked with another oral. Not appropriate for beginners.
Not well characterised in humans (an oral 17α-alkylated steroid); dosed daily, often split, in community practice.
Side Effects
Severe Hepatotoxicity
very commonA 17α-alkylated oral built on an already-potent androgen; widely regarded as one of the most liver-toxic of the prohormone-era orals even at 10-20 mg.
TUDCA, very short cycles, no alcohol, never stack with another 17-alkylated oral, and monitor liver enzymes.
Lethargy
very commonDebilitating fatigue is a signature complaint that often worsens through the cycle and forces early termination.
Keep cycles short; this is a known property of the compound, not a bad batch.
Lipid Deterioration
very commonStrongly suppresses HDL and worsens the cholesterol profile like other harsh non-aromatizing orals.
Omega-3, citrus bergamot, cardio and short duration; full recovery can take months.
HPTA Suppression
very commonA strong androgen that meaningfully suppresses natural testosterone; a testosterone base and PCT are needed.
Run a testosterone base, complete a full SERM PCT.
High Blood Pressure
commonBlood pressure commonly rises on M1T despite the lack of estrogenic water retention.
Monitor BP; telmisartan/low-dose tadalafil if needed.
General Mitigation Strategies
Treat M1T as one of the harshest oral 17-alkylated steroids: keep runs very short (2-4 weeks), never combine with another oral, avoid alcohol, and run TUDCA/NAC with liver-enzyme bloodwork. Support lipids (omega-3, citrus bergamot, cardio) and watch blood pressure. Run a testosterone base since M1T is non-aromatizing and suppressive, then complete a full SERM PCT. Finasteride does not help, like its parent DHB it is already a 5α-reduced (1-ene) androgen with no testosterone-to-DHT step to block.
Support Supplements
Ancillary supplements commonly run alongside Methyl-1-Testosterone to manage side effects, support the target tissue, or fill nutrient demands it creates.
Liver support (TUDCA + NAC)
KeyM1T is among the most hepatotoxic prohormone-era orals. TUDCA supports bile flow; NAC replenishes hepatic glutathione. Genuinely important here: but it does not make the compound safe.
- Dose
- TUDCA 1,000 mg/day; NAC 1,200 mg/day
- Timing
- Throughout the (short) cycle
Lipid support (omega-3 + citrus bergamot)
KeyM1T is harsh on HDL. Omega-3 lowers triglycerides; citrus bergamot lowers LDL via statin-like flavonoids. Support only; recovery can take months.
- Dose
- Omega-3 4 g/day; citrus bergamot 1,000 mg/day
- Timing
- With meals
Testosterone base + blood pressure support
A testosterone base supplies the estrogen M1T never makes (libido, mood, joints); telmisartan/tadalafil manage BP rise.
- Dose
- Replacement-dose testosterone; telmisartan 20-40 mg/day if BP is high
- Timing
- Throughout the cycle
Post Cycle Therapy (PCT)
M1T is non-aromatizing and strongly suppressive, so restoring natural testosterone is the goal (estrogen rebound is not the concern). Because it is short-acting, a standard SERM PCT (e.g. Nolvadex 40/40/20/20 mg/day) can begin soon after the last dose. hCG pre-PCT helps testicular recovery. Confirm rebound with bloodwork (LH, FSH, total/free testosterone), plus liver and lipid panels given its toxicity.
How It Works
M1T (methyldihydroboldenone) is a synthetic, orally active anabolic-androgenic steroid: the 17α-methyl derivative of 1-testosterone (Δ1-DHT / dihydroboldenone), i.e. 17α-methyl-5α-androst-1-en-17β-ol-3-one. Its parent 1-testosterone is a 5α-reduced, 1-ene androgen whose double bond blocks aromatase, so M1T does not convert to estrogen. It is a strong androgen-receptor agonist driving protein synthesis and nitrogen retention. The 17α-methyl group makes it orally active and, as with all 17-alkylated orals, drives its severe liver toxicity.
Hormonal & Androgenic Profile
No reliable human ratio; it is a 17α-methylated version of the potent androgen 1-testosterone/DHB and is community-regarded as far more potent by weight than methyltestosterone. Treat any specific numeric ratio as unverified.
Does not aromatize. Its parent 1-testosterone (DHB) is a 5α-reduced 1-ene androgen whose double bond blocks aromatase, so no AI is needed. The flip side is it provides none of estrogen's benefits (libido, mood, joints, lipids), which is why it is run over a testosterone base.
Like its parent DHB, M1T is already a 5α-reduced androgen (a 1-ene), so finasteride/dutasteride do nothing. There is no testosterone-to-DHT step to block, and its androgenic effects cannot be softened with 5-AR inhibitors.
Harsh on lipids (strong HDL suppression) and commonly raises blood pressure, on top of severe hepatotoxicity. No estrogenic water retention, but the liver/lipid hit defines its risk.
Fundamentals
Reference on the practices relevant to Methyl-1-Testosterone: how they are done and where they go wrong. Not a recommendation to use it.
Legal Status
Schedule III controlled substance (USA): explicitly named ("17-alpha-methyl-1-dihydrotestosterone") in the Anabolic Steroid Control Act of 2004, effective January 2005; never approved for medical use.
Legal status varies by country and changes over time. This is a general summary, not legal advice.
WADA Status
Methyl-1-testosterone is prohibited at all times as an exogenous anabolic androgenic steroid (banned from use in most major sports).