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Cabergoline vs NAD+: side-by-side comparison

Ancillary

Dostinex · Caber · Cabaser

A potent dopamine D2 receptor agonist (ergot derivative) used to control elevated prolactin levels. Essential ancillary during cycles containing 19-nor steroids (trenbolone, nandrolone) which elevate prolactin. Known for its exceptionally long half-life allowing twice-weekly dosing and its superior tolerability compared to bromocriptine.

1.0/10 natty
Full breakdown →
VS
Ancillary

Nicotinamide Adenine Dinucleotide · NAD Plus

A coenzyme essential for cellular energy and DNA repair. NAD+ levels decline with age, and supplementation may support cellular health and energy production.

1.0/10 natty
Full breakdown →

1 / 10 natty scale / 1

Same lane

Both sit in the same class and are run for health. This is a like-for-like comparison: read the gaps as real trade-offs.

The tape

Core ratings

The same three rulers every entry on the site is scored with, read head to head.

CabergolineNAD+
1.0

Natty scale

1 natural · 10 heavy

1.0
4.5

Effectiveness

Documented effect · of 5Δ1.5

3.0
2.5

Side-effect severity

Documented burden · of 5Δ1

1.5

Cost side

Body-load fingerprint

Where each one actually lands its strain, on the calculator's thirteen channels. Tap a row for what it means and which labs track it.

CabergolineNAD+

Cardiometabolic

Systemic

Injection & site care

Bars show strain at each one's typical protocol, not your dose. ≈ marks values inferred from side-effect data or category rather than hand-graded. For your numbers, run the calculator.

Logistics

The vitals

CabergolineNAD+
Ancillary
Classmatch
Ancillary
Oral
Route
Intravenous
0.5-2 mg/weekTwice weekly, split evenly (e.g., Monday/Thursday) - figures are the weekly total
Typical dose
250-1000 mg/weekTypically once per week as a single IV infusion or subcutaneous session (250-1000mg; IV is dripped over 1-4+ hours to avoid nausea/chest tightness, subq is given as one or several smaller shots). This weekly figure is maintenance dosing, some protocols (e.g. detox/addiction clinics) instead front-load with a short daily "loading" course of roughly 250-750mg/day IV for 3-10 days before tapering to a weekly maintenance dose.
63-115 hours (~80 hours average)
Half-life
Not established
4-16 weeks
Typical run
4-12 weeks
Prescription only
Legal status
OTC supplement
Not prohibited
WADAmatch
Not prohibited

Benefit side

What each is for

Shared goals carry both dots; a goal with one dot belongs to that side alone.

CabergolineNAD+
HealthPCTLongevityRecovery

Run for

Prolactin Control During 19-Nor CyclesEssential for controlling prolactin elevation caused by trenbolone, nandrolone (deca), and other progestogenic compounds.
Sexual Function RestorationRestores libido, erectile function, and gonadal function suppressed by hyperprolactinemia. Clinical studies (e.g., De Rosa et al.) document significant improvement in sexual potency and testosterone status within months of treatment.
Gynecomastia PreventionPrevents prolactin-induced gynecomastia which can occur independently of estrogen-related gyno.
Refractory Period ReductionCommonly reported to reduce male refractory period after orgasm due to prolactin suppression.

Documented upside

  • Normalizes prolactin in 86-92% of patients (Verhelst 1999, 455-patient study)
  • Exceptionally long half-life allows twice-weekly dosing
  • Superior tolerability vs bromocriptine (fewer GI side effects)
  • Effects begin within 3 hours, last up to 7 days
  • Restores libido and sexual function suppressed by high prolactin
+3 more on the full page

Run for

Cellular EnergySupports mitochondrial function and ATP production.
Anti-AgingMay slow aspects of cellular aging through sirtuin activation.
DNA RepairSupports DNA repair mechanisms.

Documented upside

  • Enhanced cellular energy
  • Improved mental clarity
  • Potential anti-aging effects
  • DNA repair support
  • Mitochondrial health

The downsides

Side effects, aligned

Each entry's documented side effects, sorted onto the same body systems so the gaps and the overlaps are visible. Tap any effect for the detail.

CabergolineNAD+
Blood pressure & water

None documented

Heart

None documented

None documented

Mood, sleep & CNS

None documented

Injection site
Other documented effects

The exit

Hormonal fallout & recovery

What each does to your own hormone axis while on, and what leaving it costs.

CabergolineNAD+
Not required
PCT
Not required
Support role
What sticks
Support role

Cabergoline

Cabergoline is an ancillary compound used during cycle, not a PCT drug. It does not affect the HPT axis directly. Continue use during PCT if prolactin is still elevated. Can be discontinued once prolactin normalizes.

NAD+

Not hormonal. No PCT required.

Read-out

How they separate

  1. 01

    Enhancement

    They land at almost the same point on the natty scale (1/10 vs 1/10): a similar distance beyond natural.

  2. 02

    Side-effect bill

    Cabergoline's documented side-effect severity is heavier (2.5/5 vs 1.5/5). The body-load fingerprint above shows where that weight actually lands.

  3. 03

    Body load

    The widest gap at typical protocols is blood pressure (Cabergoline 2.8/10 vs 0/10), then mood & sleep (NAD+ 2.2/10 vs 0/10).

  4. 04

    Coming off

    Neither requires PCT: both leave the natural testosterone axis running.

  5. 05

    Logistics

    Cabergoline runs as oral, NAD+ as intravenous; typical runs are 4-16 weeks vs 4-12 weeks.

Generated from each entry's data file. Descriptive, not a recommendation; nothing here is medical advice.

Full breakdownCabergoline→Full breakdownNAD+→

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