Skip to content

Finasteride vs NAD+: side-by-side comparison

Ancillary

Propecia · Proscar · Fin

A 5-alpha reductase inhibitor that blocks the conversion of testosterone to DHT, reducing serum DHT by 65-70%. Used during testosterone cycles to prevent DHT-related hair loss. CRITICAL: Only works with testosterone-based compounds. Does NOT work with DHT derivatives (Masteron, Winstrol, Anavar). Makes hair loss WORSE with nandrolone compounds.

1.0/10 natty
Full breakdown →
VS
Ancillary

Nicotinamide Adenine Dinucleotide · NAD Plus

A coenzyme essential for cellular energy and DNA repair. NAD+ levels decline with age, and supplementation may support cellular health and energy production.

1.0/10 natty
Full breakdown →

1 / 10 natty scale / 1

Same lane

Both sit in the same class and are run for health. This is a like-for-like comparison: read the gaps as real trade-offs.

The tape

Core ratings

The same three rulers every entry on the site is scored with, read head to head.

FinasterideNAD+
1.0

Natty scale

1 natural · 10 heavy

1.0
4.0

Effectiveness

Documented effect · of 5Δ1

3.0
2.5

Side-effect severity

Documented burden · of 5Δ1

1.5

Cost side

Body-load fingerprint

Where each one actually lands its strain, on the calculator's thirteen channels. Tap a row for what it means and which labs track it.

FinasterideNAD+

Hormonal

Systemic

Injection & site care

Bars show strain at each one's typical protocol, not your dose. ≈ marks values inferred from side-effect data or category rather than hand-graded. For your numbers, run the calculator.

Logistics

The vitals

FinasterideNAD+
Ancillary
Classmatch
Ancillary
Oral
Route
Intravenous
1-5 mg/dayOnce daily
Typical dose
250-1000 mg/weekTypically once per week as a single IV infusion or subcutaneous session (250-1000mg; IV is dripped over 1-4+ hours to avoid nausea/chest tightness, subq is given as one or several smaller shots). This weekly figure is maintenance dosing, some protocols (e.g. detox/addiction clinics) instead front-load with a short daily "loading" course of roughly 250-750mg/day IV for 3-10 days before tapering to a weekly maintenance dose.
5-6 hours (plasma)
Half-life
Not established
12-52 weeks
Typical run
4-12 weeks
Prescription only
Legal status
OTC supplement
Not prohibited
WADAmatch
Not prohibited

Benefit side

What each is for

Shared goals carry both dots; a goal with one dot belongs to that side alone.

FinasterideNAD+
HealthCosmeticLongevityRecovery

Run for

Hair Loss Prevention During Testosterone CyclesBlocks conversion of testosterone to DHT, preventing DHT-mediated hair follicle miniaturization. Only effective with testosterone-based compounds.
Prostate ProtectionReduces prostatic DHT by 80-90%. PCPT trial showed 25% reduction in prostate cancer risk. Prevents testosterone-induced prostate enlargement.
Preserving Testosterone LevelsBy blocking DHT conversion, may increase circulating testosterone by ~15%, remaining within the normal physiologic range.

Documented upside

  • Reduces serum DHT by 65-70%
  • FDA Propecia 5-year trials: 90% of men had no further hair loss (48% regrowth, 42% no change)
  • May increase circulating testosterone by ~15% (still within physiologic range)
  • Does NOT impair muscle gains from testosterone (12-month RCT confirmed)
  • 25% reduction in prostate cancer risk (PCPT trial)
+3 more on the full page

Run for

Cellular EnergySupports mitochondrial function and ATP production.
Anti-AgingMay slow aspects of cellular aging through sirtuin activation.
DNA RepairSupports DNA repair mechanisms.

Documented upside

  • Enhanced cellular energy
  • Improved mental clarity
  • Potential anti-aging effects
  • DNA repair support
  • Mitochondrial health

The downsides

Side effects, aligned

Each entry's documented side effects, sorted onto the same body systems so the gaps and the overlaps are visible. Tap any effect for the detail.

FinasterideNAD+
Estrogenic

None documented

Mood, sleep & CNS

None documented

Injection site
Other documented effects

The exit

Hormonal fallout & recovery

What each does to your own hormone axis while on, and what leaving it costs.

FinasterideNAD+
none
HPTA suppression
No data
none
Aromatization
No data
none
Liver toxicity
No data
none
Hair-loss risk
No data
No
DHT-derived
No data
No
19-nor / progestogenic
No data
Not required
PCT
Not required
Support role
What sticks
Support role

Finasteride

Does not affect HPT axis directly. No PCT required. Can be used long-term. May slightly increase testosterone by blocking DHT conversion.

NAD+

Not hormonal. No PCT required.

Read-out

How they separate

  1. 01

    Enhancement

    They land at almost the same point on the natty scale (1/10 vs 1/10): a similar distance beyond natural.

  2. 02

    Side-effect bill

    Finasteride's documented side-effect severity is heavier (2.5/5 vs 1.5/5). The body-load fingerprint above shows where that weight actually lands.

  3. 03

    Body load

    The widest gap at typical protocols is estrogen load (Finasteride 1.8/10 vs 0/10).

  4. 04

    Coming off

    Neither requires PCT: both leave the natural testosterone axis running.

  5. 05

    Logistics

    Finasteride runs as oral, NAD+ as intravenous; typical runs are 12-52 weeks vs 4-12 weeks.

Generated from each entry's data file. Descriptive, not a recommendation; nothing here is medical advice.

Full breakdownFinasteride→Full breakdownNAD+→

More matchups

Dutasteride vs FinasterideFinasteride vs TUDCAFinasteride vs GlutathioneNAD+ vs TUDCANAD+ vs Glutathione